When in 1979 six research groups independently described a 53 kDa protein, none of the participants suspected to which genetic superstar this protein would develop. This protein, which due to its molecular weight was given the not-so-impressive name p53, is perhaps the most important policeman in our cells; but only as long as it works properly. If p53 loses its functionality, it’s getting pretty dangerous. In fact, no other gene is mutated more frequently in tumor cells than p53. So how does normal p53 manage to keep all of our body cells in check and what does it all have to do with CRISPR?… Read more
- AAVs ACE2 ACE inhibitors Angiotensin Brain Bsx camostat mesylate childhood dementia Coronavirus CRISPR Development Disease Dissertation DNA repair Drosophila enzyme replacement therapy Fly Room Gene Therapy genetic compensation Hamburg Homeobox Homeotic Mutations Hypothalamus Josef Penninger knock-down knock-out Lungs Lysosome Neuroanatomy oligonucleotides Pandemic personalized medicine Pineal Gland pneumocytes recombinant proteins Renin René Descartes SARS-CoV2 SRY Thesis TMPRSS2 Transcription Factor Upf3a Virus Zebrafish
of the Special Prize of the Editor for the best Science Blog in 2019 by “Wissenschaft kommuniziert“
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