Thank you very much for your keen interest in my article from last week in which I explained that SARS-CoV-2 binds to the ACE2 protein on our cell surfaces so that it can enter our cells together with ACE2 itself. Over the last few weeks you have probably read quite a few times that Covid-19 often isn’t just cause an infection of the lungs, but probably affects many other tissues as well. Usually this is attributed to ACE2 being present in many other tissues. The idea behind it: all cells that carry ACE2 can be infected by SARS-CoV2. Well, today I would like to explain why it’s not that simple. If we look at the viral entry process in more detail, we find that at first only a part (the S1 part) of the spike protein binds to the ACE2 receptor and then…… Read more
- AAVs ACE2 ACE inhibitors Angiotensin Brain Bsx camostat mesylate childhood dementia Coronavirus CRISPR Development Disease Dissertation DNA repair Drosophila enzyme replacement therapy Fly Room Gene Therapy genetic compensation Hamburg Homeobox Homeotic Mutations Hypothalamus Josef Penninger knock-down knock-out Lungs Lysosome Neuroanatomy oligonucleotides Pandemic personalized medicine Pineal Gland pneumocytes recombinant proteins Renin René Descartes SARS-CoV2 SRY Thesis TMPRSS2 Transcription Factor Upf3a Virus Zebrafish
of the Special Prize of the Editor for the best Science Blog in 2019 by “Wissenschaft kommuniziert“
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